Given the tough moment that Monterrey is going through, the match on Wednesday will be an opportunity for Santos Laguna to achieve its first victory in Rayados' current stadium.
The Lagunero team will face the regiomontano in the quarter-finals of the Copa MX, aiming to break the streak of matches without defeating La Pandilla as visitors.
The last time the Guerreros defeated Rayados as visitors was a match in the Copa MX Apertura 2014, in which they secured a 3-2 victory.
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After that, Santos visited Monterrey again, but this time in the new stadium, in August 2015, and a 1-1 draw was registered.
The Laguneros have visited the regiomontano team seven times in their recently opened stadium, with a record of five victories for the home team and two draws.
Currently, Monterrey is looking to overcome the difficult moment they are going through in the current national soccer tournament, in which they have only earned three points out of 18 possible. The Copa MX match is seen as a chance to boost their morale.
For the visitors, taking advantage of the momentum of Antonio Mohamed's team will allow them to achieve their first victory in the current home stadium of the regiomontano team, and in the process, continue their quest for the Copa MX title.