That’s according to Blues defender Cesar Azpilicueta.
The two sides meet for the first time in six years in the first leg of the Champions League last 16.
But the home fans are still hurting from their clash three years prior to that.
With Guus Hiddink in charge, the Premier League giants were leading at Stamford Bridge and on course to reach their second successive European final.
However they had their hearts broken when Iniesta fired home a crucial away goal deep into stoppage time.
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Barcelona’s likely line-up to face Chelsea away
FC BARCELONA
“I think Andres continues to generate nightmares and I do not think we will get a good reception.”
Chelsea defender Cesar Azpilicueta
Chelsea got their revenge by knocking Barca out of the semi-final on their way to their only Champions League title in 2012.
But Azpilicueta has warned Iniesta to expect hostility from the supporters.
"I remember that I was in Osasuna when he scored that goal to take Barcelona to the final in Rome," he told AS.
"That changed his history so much and I think the Chelsea fans still feel that in their hearts.
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"I think Andres continues to generate nightmares and I do not think we will get a good reception."
Antonio Conte is under pressure as Chelsea boss and will be hoping to progress in the Champions League to resurrect a disappointing season.
They’re currently fourth in the Premier League, three points behind second-placed Manchester United, who they meet at Old Trafford on Sunday.